Dear Michiel and John
Many thanks for your responses so far. They have been extremely helpful.
I wanted to run a sequential design with some two way interactions. Below is my syntax:
design
;alts = alt1, alt2
;rows = 16
;orth = seq
;block=2
;model:
U(alt1) = b1*A[0,1,2,3,4,5,6,7] + b2*B[0,1,2,3] + b3*C[0,1,2,3] + b4*D[0,1,2,3,4,5,6,7] + b5*E[0,1,2,3] + b6*A*B + b7*B*C/
U(alt2) = b1*A + b2*B + b3*C + b4*D + b5*E + b6*A*B + b7*B*C$
Ngene crashed when I ran the code above.
If I delete the line ';block=2' then I can get a design but the two interaction terms are highly correlated with the main effects within the same alternatives which is not ideal.
So is blocking not allowed in this case?
I went on using the 'foldover' option. It allowed using blocking and also gave me a design whose interaction terms are uncorrelated with the main effects within the same alternatives.
Can I confirm with you that this design can be used to estimate coefficients of interaction terms? Also, can I use my own blocking and ignore 'foldover block''?
Many thanks,
Yuanyuan